Principal Investigator: Carlos J. Blondel, PhD.
Carlos is a biochemist from Universidad de Chile, same place where he obtained his PhD in 2011 working under the mentorship of Dr. Inés Contreras and Dr. Carlos Santiviago, studying both the regulation of LPS biosynthesis in Shigella flexneri and Salmonella enterica and the identification of Type VI Secretion Systems in Salmonella.
In 2013, he was named PEW Latin American Fellow in the Biomedical Sciences and he joined the laboratory of HHMI Investigator Dr. Matthew K. Waldor at Harvard Medical School and Brigham and Women´s Hospital for his postdoctoral trainning. During his postdoctoral trainning under Dr. Waldor´s mentorship, he studied the molecular mechanisms that underlie the virulence of bacterial pathogens such as the pandemic Vibrio parahaemolyticus O3:K6 and Enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 and he used CRISPR/Cas9-based genetic screens to identify host factors that promote human susceptibility to the toxic action of Vibrio parahaemolyticus' two Type III Secretion Systems (T3SS).
In 2017, he was selected as an HHMI-Gulbenkian International Research Scholar. Dr. Blondel currently investigates the emergence of human pathogens by studying their molecular weaponry and how virulence emerges from coincidental evolution due to their adaptation to the environment and their respective ecological niches.
In 2019 he joined the Institute of Biomedical Sciences at Universidad Andrés Bello (ICB-UNAB).
Verónica is a Veterinarian and has a PhD in Biomedical Sciences from Universidad de Chile. Her research is focused in understanding the mechanisms that underlie the emergence and transmission of zoonotic agents from the animal to the human host. In our lab she is currently working on the pathogenesis and genomic epidemiology and antimicrobial resistance of clinical Campylobacter jejuni and Campylobacter coli in Chile.
Italo is a Biochemist and holds a Masters degree from Universidad Nacional Andres Bello and a PhD in Biochemistry from Universidad de Chile. In his PhD he worked under the supervision of Dr. Carlos Santiviago studying the mechanisms behind the manipulation of Dictyostelium discoideum and murine macrophages by Salmonella Typhimurium. In our lab he is currently working studying the mechanisms behind the cell death induced by the T3SS2 of Vibrio parahaemolyticus.
Sebastián is a Biochemist and holds a Masters degree from Universidad Nacional Andres Bello. He is currently enrolled in the Molecular Biosciences PhD program at UNAB. He worked as an undergraduate at the laboratory of Dr. Guido Mora studying how MarT regulates S. Typhi. In our lab he is currently working studying the interaction of Vibrio parahaemolyticus with bacteriovorus protists.
Nicolás is a Biotechnology Engineer and currently a graduate student from the PhD program in Biomedical Sciences of Universidad Autónoma de Chile. In our lab he is currently working on novel effector proteins from the T3SS2 of Vibrio parahaemolyticus.
Pablo holds a Bachelors degree in Biochemistry from University of Chile. Has worked studying the regulatory mechanisms of LPS synthesis in enterobacteria. In addition to the important task of been our lab manager, he is also currently working studying novel components and effectors of the T3SS2 of V. parahaemolyticus.
Past Lab Members
Universidad San Sebastián
Universidad de la Frontera
PhD. Biomedical Sciences
Universidad Autónoma de Chile
Join the Blondel Lab!
If you are intrigued about microbes and want to tackle some of the most interesting unsolved problems in infectious disease research, you have come to the right place!
Undergraduate and Graduate students:
We look forward to welcoming rotation students to the lab.
We welcome applications from highly motivated researchers. We currently have funding for undergratuated, graduate and selected Postdoctoral fellows.
For additional funding candidates can also apply to Chile's FONDECYT Postdoctoral Grants. Please contact us if you are interested to join our lab. The deadline for FONDECYT grants are on august of each year. More info in this link.
Interested in joining the team?
Send an email to carlos.blondel(at)unab.cl !